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ARPIMUNE-O 100 MG

CYCLOSPORINE CAPSULES 100 MG

MRP	:	~~MRP ₹541.25~~
Price	:	₹250.00
You Save	:	₹291.25 (53.81%)

5 capsule(s) in a strip

SKU: 371 Category: Derma/ Skin & Body Care Tag: DERMA/ SKIN BODY CARE Brand: RPG LIFE SCIENCES LTD

Arpimune-O 100mg Capsule, containing the active ingredient Cyclosporine, is an immunosuppressant primarily prescribed to prevent organ rejection in patients who have undergone organ transplantation, such as kidney, liver, or heart transplants. It works by mitigating the body’s aggressive immune response, which recognizes the transplanted organ’s antigens as foreign, thus helping to prevent the rejection of the new organ by the body’s immune system when used in conjunction with other medicines. However, it’s crucial to be aware that immunosuppressants like Arpimune-O 100mg Capsule can increase the risk of skin cancer, necessitating limited sun exposure, the use of protective clothing, and high SPF sunscreen. Patients should also inform their physician if they have recently received live vaccinations. This medication is contraindicated in individuals with known hypersensitivity or allergy to Cyclosporine or its components and should be used cautiously or avoided in those with uncontrolled high blood pressure or a history of hypertension, as it can raise blood pressure levels. Furthermore, it is important to discuss potential reproductive effects with a healthcare professional, especially for individuals planning to conceive, and regular diabetes monitoring is essential, particularly for those at risk.

Prevention of organ rejection (Kidney, liver, and heart)
Treatment of Rheumatoid arthritis and Psoriasis

Arpimune-O 100mg Capsule, through its active ingredient Cyclosporine, effectively prevents organ rejection in transplant recipients by specifically targeting and suppressing the immune system. Following an organ transplant, the recipient's immune system identifies the new organ's antigens as foreign, initiating a robust immune response aimed at attacking and rejecting it. Cyclosporine intervenes in this process by inhibiting the activation of T-cells, a crucial type of white blood cell that plays a central role in orchestrating immune responses. More precisely, Cyclosporine binds to an intracellular protein called cyclophilin, and this complex then inhibits calcineurin, an enzyme vital for T-cell activation. By preventing calcineurin from functioning, Cyclosporine stops the dephosphorylation of NFAT (nuclear factor of activated T-cells), which is necessary for NFAT to enter the cell nucleus and initiate the transcription of interleukin-2 (IL-2) and other cytokines. Since IL-2 is a key growth factor for T-cells, its reduced production effectively dampens T-cell proliferation and differentiation. This targeted suppression of T-cell activity helps to prevent the immune system from attacking and damaging the transplanted organ, thereby significantly enhancing the chances of successful organ transplantation.

It is crucial to provide your healthcare provider with a comprehensive list of all medications you are currently taking. This includes not only prescription medications but also over-the-counter drugs, nutritional and vitamin supplements, and any herbal products. The reason for this thorough disclosure is that certain medications can interact with Arpimune-O 100mg Capsule, potentially reducing its effectiveness or leading to undesirable side effects. A complete understanding of your current medication regimen allows your healthcare provider to identify and manage any potential interactions, ensuring the safe and effective use of Arpimune-O 100mg Capsule in your treatment plan.

Arpimune-O 100mg Capsule is an orally administered prescription medication, meaning it can only be obtained with a doctor's order. Your physician will determine the precise dosage and duration of your Arpimune-O 100mg Capsule treatment, taking into account your specific medical condition, as well as individual factors such as your body weight and age. It is paramount that you strictly adhere to your doctor's instructions when taking this medicine. To maintain consistent medication levels in your body, always take the tablet at the same time each day, and it can be taken either with or without food. Importantly, you should never attempt to break, chew, or crush the tablet; instead, swallow the entire tablet whole with a glass of water to ensure its proper delivery and absorption.

Store this medication below 30°C
Protect the medicine from light and excessive moisture.
Keep the medicine out of reach of children and pets
Take only a partial dose to make up for a forgotten dose.

Serious

Kidney damage
Liver damage
Infection, fever or sore throat
Lack of coordination
Memory problems
Difficulty in speaking
Visual problems
Seizures
Confusion
Personality changes
Sleeplessness
Agitation

Common

Hypertension
Electrolyte imbalance
Increased level of potassium in the blood
Tremor
Abnormal hair growth
Enlargement of gum tissues
Low levels of magnesium
Risk of infections
Headache
Gastrointestinal disturbances

Breast Feeding

Unsafe

Arpimune-O 100mg Capsule can pass into breast milk. Mothers receiving treatment with it should not breastfeed.

Alcohol

Unsafe

It is unsafe to drink alcohol while taking Arpimune-O 100mg Capsule. It may reduce the drug's effectiveness and can cause toxic side effects.

Liver

Unsafe

Arpimune-O 100mg Capsule should be used cautiously in individuals with liver impairment or pre-existing liver disease. This is because this medication is primarily metabolized in the liver, and impaired liver function can affect the metabolism and clearance of the medication from the body.

Lungs

Consult Your Doctor

It is unknown whether Arpimune-O 100mg Capsule can be administered in patients with lung diseases. Inform your physician if you have any lung diseases before initiating the therapy.

Driving

Unsafe

Arpimune-O 100mg Capsule can cause dizziness. It is recommended to avoid driving and operating heavy machinery during the treatment.

Pregnancy

Consult Your Doctor

If you are taking Arpimune-O 100mg Capsule and are planning to become pregnant or are already pregnant, it is important to discuss this with your healthcare professional.