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FOLICULIN 75

UROFOLLITROPIN INJECTION 75 IU

2-8* C

MRP	:	~~MRP ₹1,045.66~~
Price	:	₹500.00
You Save	:	₹545.66 (52.18%)

1 vial(s)

SKU: 347 Category: Gynaecology Tags: COLD CHAIN, Gynaecology Brand: BHARAT SERUMS & VACCINES

Foliculin 75IU Injection, containing the active substance Urofollitropin, is an ovulation stimulator that belongs to the class of medications known as gonadotropins. Its primary use is to address infertility in women who are not ovulating, including those with polycystic ovarian disease, especially when they have not responded to prior treatment with clomiphene citrate. It also plays a crucial role in promoting fertility by helping to develop multiple follicles in women undergoing assisted reproductive technologies such as IVF (in-vitro fertilization) or other forms of assisted conception. Furthermore, this injection is indicated for the treatment of infertility in men caused by a low sperm count.

However, there are important contraindications for Foliculin 75IU Injection. You should not take this medicine if you are allergic to Urofollitropin or any of its other ingredients. It is also contraindicated if you have a tumor in the pituitary gland (a gland at the base of the brain that produces certain hormones, including growth hormones), the hypothalamus (an area under the thalamus that controls bodily conditions like temperature and blood pressure), or in the uterus, ovaries, breast, testicles, or prostate gland. Before starting treatment, your doctor will perform checks for underactive thyroid problems, assess hormone levels, and screen for tumors of the pituitary and hypothalamus.

Additionally, Foliculin 75IU Injection should not be taken if you have ovarian cysts not attributed to PCOD, unexplained vaginal bleeding, early menopause, physical problems with your reproductive organs, if your womb has been surgically removed, or if you are pregnant or breastfeeding. It is imperative to inform your physician immediately if you experience any symptoms such as abdominal pain and swelling, weight gain, diarrhea, difficulty breathing, or decreased urination, as these could indicate serious complications. Lastly, inform your physician if you have pre-existing liver problems or a history of blood clotting disorders before beginning treatment with Foliculin 75IU Injection.

Infertility in women

Foliculin 75IU Injection contains Urofollitropin, which is a highly purified form of follicle-stimulating hormone (FSH). While the previous statement correctly notes its role in treating infertility in women and mentions LH receptors, the primary and direct mechanism of Urofollitropin is focused on FSH.

Here's a more precise explanation of how Foliculin 75IU Injection works:

Foliculin 75IU Injection (Urofollitropin) works by directly binding to the follicle-stimulating hormone (FSH) receptors located on the surface of granulosa cells within the ovarian follicles. This binding initiates a series of intracellular events that promote:

Follicular Growth and Development: FSH is the primary hormone responsible for initiating and sustaining the growth of ovarian follicles, which house and nourish developing eggs. By providing exogenous FSH, Foliculin 75IU stimulates the maturation of these follicles.
Estrogen Production: As follicles grow under FSH stimulation, their granulosa cells produce estrogen. This increase in estrogen is crucial for preparing the uterus for potential pregnancy and plays a role in the overall ovarian response.
Ovulation (with hCG): While Urofollitropin stimulates follicular development, it generally doesn't directly trigger ovulation on its own. In most treatment protocols, once the follicles reach an adequate size and maturity (often monitored by ultrasound and estrogen levels), another hormone, human chorionic gonadotropin (hCG), is administered. hCG mimics the natural luteinizing hormone (LH) surge and acts on the LH receptors, causing the final maturation and release of the egg(s) from the mature follicle(s) (ovulation).

Therefore, Foliculin 75IU Injection primarily works by providing the necessary FSH stimulation to promote follicular development, and when combined with a subsequent hCG trigger, it leads to ovulation, thereby treating infertility in women. While the extract mentions LH receptors, Urofollitropin itself is primarily FSH, and the LH effect for ovulation is typically mediated by a separate hCG injection.

It is extremely important to provide your healthcare provider with a comprehensive list of all medications you are currently taking or have taken recently. This includes not only prescription medications but also over-the-counter drugs, any recent vaccinations, nutritional and vitamin supplements, and all herbal products. The reason for this thorough disclosure is that certain medications can interact with Foliculin 75IU Injection. Such interactions could potentially reduce the effectiveness of Foliculin 75IU Injection or lead to undesirable side effects, which could compromise your fertility treatment and well-being. Your healthcare provider needs this information to identify and manage any potential interactions, thereby ensuring the safest and most effective use of Foliculin 75IU Injection for your condition.

Foliculin 75IU Injection will be given to you by a doctor or nurse in a hospital or clinic setting. It is given as an intramuscular injection (into your muscles) or under the skin. Do not self-administer the injection. Your doctor will decide the dose, route of administration and duration of the treatment based on your disease severity, body weight, and other factors.

Store Foliculin 75IU Injection between (2°C to 8°C)
Do not freeze.

Common

Abdominal pain or swelling
Headache
Nausea
Pelvic pain
Overstimulation of ovaries
Pain or inflammation at the injection site
Mood swings

Serious

Severe allergic reactions (hypersensitivity reactions)

Breast Feeding

Unsafe

Breastfeeding is not recommended in patients taking Foliculin 75IU Injection because the medicine passes into the breast milk in small amounts and may harm your baby.

Alcohol

Consult Your Doctor

It is unknown whether consuming alcohol is safe during the treatment with Foliculin 75IU Injection. Inform your doctor if you are a chronic drinker.

Liver

Consult Your Doctor

It is unknown whether Foliculin 75IU Injection can be used in patients with liver disorders. Consult your doctor if you have any liver problems before starting the treatment.

Lungs

Consult Your Doctor

It is unknown whether Foliculin 75IU Injection can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.

Driving

Safe

Foliculin 75IU Injection does not affect the ability to drive. If you feel tired or dizzy after taking this medicine, do not drive and consult your doctor for more advice.

Pregnancy

Unsafe

Foliculin 75IU Injection is unsafe to administer in pregnant women because it may affect the fetus. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant.