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enfira 500

Name: enfira 500
Brand: Zydus Lifesciences Limited
SKU: 034
Availability: InStock

RITUXIMAB INJECTION 500MG/50ML

2-8* C

MRP	:	~~MRP ₹39,992.34~~
Price	:	₹8,000.00
You Save	:	₹31,992.34 (80%)

1 vial(s) of 50ml

SKU: 034 Categories: Anti-Cancer, Anti-Cancer Drugs, CANCER Tag: cancer Brand: Zydus Lifesciences Limited

Enfiera 500mg Injection contains rituximab as its active ingredient and is used to treat several conditions in adults. It may be used alone or in combination with other medications to treat non-Hodgkin’s lymphoma (a cancer of B-lymphocytes) and chronic lymphocytic leukemia (a common cancer affecting B-cells). It is also prescribed in combination with methotrexate to treat moderate-to-severe rheumatoid arthritis in adults, where the immune system mistakenly attacks the joints.

Other approved uses include the treatment of granulomatosis with polyangiitis and microscopic polyangiitis—inflammatory diseases affecting blood vessels, primarily in the lungs and kidneys—in both adults and children aged 2 years and older. Additionally, it is used to manage moderate-to-severe pemphigus vulgaris, an autoimmune condition that causes painful blisters on the skin and mucous membranes of the mouth, throat, nose, and genitals.

Enfiera belongs to a class of medicines known as anti-CD20 monoclonal antibodies. You should not receive this injection if you are allergic to rituximab or any of its ingredients, have a weakened immune system, or are suffering from a serious active infection. Inform your doctor if you have a history of heart conditions, heart failure, or breathing issues. Also, let your physician know if you’ve ever had a hepatitis B infection, as this virus can reactivate during treatment and lead to serious complications.

Pregnancy and breastfeeding are not advised during treatment with Enfiera. Effective contraception must be used during therapy and for 12 months after the final dose if you are able to conceive.

Common side effects include blood infections, anemia, dizziness, facial and body swelling, itchy skin, diarrhea, increased sweating, and changes in blood pressure. This medicine can also cause severe infusion reactions, which may occur during or within 24 hours after administration. Inform your healthcare provider immediately if you experience symptoms such as high or low blood pressure, chest pain, headache, difficulty breathing, vomiting, rashes, or throat swelling during or after the infusion.

Non-hodgkin’s lymphoma (NHL)
Chronic lymphocytic leukemia (CLL)
Rheumatoid Arthritis
Granulomatosis with polyangiitis or microscopic polyangiitis
Pemphigus vulgaris

Enfiera 500mg Injection is a monoclonal antibody that specifically targets the CD20 antigen found on the surface of B-lymphocytes (a type of white blood cell). By binding to these B-cells, the medicine triggers their destruction, which is essential in treating non-Hodgkin’s lymphoma (NHL) and chronic lymphocytic leukemia (CLL). This binding blocks B-cell activation and proliferation, contributing to its anticancer effects.

In rheumatoid arthritis, Enfiera works by suppressing the immune response. It reduces the production of rheumatoid factor, inhibits antigen presentation, limits T-cell activation, and decreases the release of proinflammatory cytokines, helping to control inflammation and joint damage.

It is important to inform your healthcare provider about every medication you are taking or have recently taken. This includes prescription medications, non-prescription or over-the-counter drugs, nutritional supplements, vitamins, and any herbal or traditional remedies. Sharing this information is essential to ensure your safety during treatment with Enfiera 500mg Injection.

In particular, you should let your doctor know if you are using medications that are meant to manage blood pressure, treat heart diseases, or support cardiovascular function. This is because certain medicines can interact negatively with Enfiera, potentially reducing how well it works or increasing the risk of adverse side effects. By providing your doctor with a complete list of your medications, they can make more informed decisions to adjust your treatment plan and avoid harmful interactions.

Enfiera 500mg Injection should only be administered by a qualified and experienced healthcare professional, such as a trained doctor or nurse, in a clinical setting. It is strictly advised that you do not attempt to self-administer this injection, as it requires proper technique and medical supervision to ensure safe and effective delivery.

Before administering the Enfiera injection, your healthcare provider will give you pre-medications, which may include antihistamines, corticosteroids, or fever-reducing drugs. These are intended to minimize the risk of infusion-related side effects that may occur during or after the treatment.

The appropriate dose and duration of your therapy will be carefully determined by your doctor. This decision will depend on various factors, including the type and severity of your condition, your overall health status, and how well you respond to the treatment.

Enfiera 500mg will be delivered through an intravenous (IV) infusion, meaning it is slowly injected into a vein over a specific period of time. During and after the infusion, you will be closely monitored by medical staff to detect and manage any potential adverse reactions promptly.

Store Enfiera 500mg injection in the refrigerator (2°C to 8°C)
Do not freeze
keep the injection away from the reach of children and pets.
If you have missed any dosing appointments, inform your doctor and schedule immediately.

Common

Swelling in the face and body
Diarrhea and nausea
Itchy skin
Anemia
Muscle spasm
Headache
Urinary tract infection
Fever, chills, and shivering
Inflammation of nasal cavities
Cough, sore throat
Loss of hair

Serious

Increased or decreased blood pressure
Chest pain
Hypersensitivity reactions
Hepatitis B viral infection
Memory loss, trouble thinking, difficulty in walking

Breast Feeding

Unsafe

Breastfeeding is not recommended in patients taking Enfiera 500mg injection because the medicine passes into the breast milk in small amounts and may harm your baby.

Alcohol

Unsafe

Consuming alcohol may affect the effectiveness of Enfiera 500mg injection. Stop consuming alcohol if you are taking this medicine.

Liver

Consult Your Doctor

Whether Enfiera 500mg injection can be used in patients with liver impairment is unknown. Consult your doctor if you have or ever had liver disease or hepatitis B infection before starting the treatment. The reactivation of hepatitis viral infection can cause severe liver problems.

Lungs

Consult Your Doctor

It is unknown whether Enfiera 500mg injection can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.

Driving

Unsafe

Caution is required while driving and operating machinery when you take Enfiera 500mg injection because it may cause dizziness, sleepiness, tiredness, and risk of falling.

Pregnancy

Unsafe

Enfiera 500mg injection is unsafe to administer in pregnant women because it may affect the fetus. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant. Using an effective birth control method during the treatment and for 12 months after your last dose is necessary.