- Fungal infections of one or more deep organs of the body
- Suspected fungal infections
- Visceral leishmaniasis
AMPHONEX 50MG
MRP | : |
|
Price | : | ₹1,500.00 |
You Save | : | ₹5,602.12 (78.88%) |
1 vial(s)
MRP | : |
|
Price | : | ₹1,500.00 |
You Save | : | ₹5,602.12 (78.88%) |
1 vial(s)
The mechanism of action for Amphonex 50mg injection, which contains Liposomal Amphotericin B, relies on its specific interaction with fungal cell membranes. The active component, Amphotericin B, primarily binds to ergosterol, a sterol that is a vital structural component of fungal cell membranes. This binding is crucial because mammalian cells primarily use cholesterol in their membranes, making ergosterol a selective target for the drug.
Once Amphotericin B binds to ergosterol, it disrupts the integrity of the fungal cell membrane. This disruption leads to changes in membrane permeability, causing the formation of pores or channels. As a result, essential intracellular contents, such as ions (like potassium and magnesium), amino acids, and other vital small molecules, leak out of the fungal cell. This uncontrolled leakage severely compromises the cell's metabolic processes and internal environment, ultimately leading to fungal cell death. The liposomal formulation helps to deliver the drug more specifically to fungal cells, which can reduce toxicity compared to conventional amphotericin B.
A doctor or nurse will administer this medication to you exclusively in a hospital or clinic setting. It is given as an intravenous infusion drip, meaning it will be delivered directly into your vein. It is crucial that you do not attempt to self-administer this injection. Your doctor will determine the appropriate dose and duration of the treatment, basing these decisions on the severity of your disease, your body weight, and other relevant medical factors
Common
Serious
It is unknown whether Amphonex 50mg injection is safe for breastfeeding women. Inform your physician if you are breastfeeding before initiating the treatment.
It is unknown whether consuming alcohol is safe during the treatment with Amphonex 50mg injection. Inform your doctor if you are a chronic drinker
It is unknown whether Amphonex 50mg injection can be used in patients with liver disorders. Consult your doctor if you have any liver problems before starting the treatment.
It is unknown whether Amphonex 50mg injection can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.
Amphonex 50mg injection may affect your ability to drive and operate machinery. Do not drive or use heavy machinery during the treatment.
Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant before receiving Amphonex 50mg injection.
Molecule Name: Liposomal Amphotericin B
Therapeutic Class: Antibiotic
Pharmacological Class: Antifungals
Indications:
1. Fungal infections of one or more deep organs of the body
2. Suspected fungal infections
3. Visceral leishmaniasis
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