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10 tablet(s) in a strip
Anvimo 240mg Tablet is an antiviral drug that contains letermovir as its active component. It falls under the category of antiviral agents and is specifically classified as a cytomegalovirus (CMV) DNA terminase inhibitor. This tablet is mainly utilized to prevent CMV infection in patients who have recently had an allogeneic hematopoietic stem cell transplant (HSCT) and are at an increased risk of CMV reactivation.
The mechanism of Anvimo 240mg Tablet involves the inhibition of the CMV DNA terminase complex, which is essential for the replication of the virus. It is generally prescribed for adult patients who are CMV-seropositive following transplantation to minimize the risk of viral complications. However, it is important to note that this medication does not treat existing CMV infections.
Patients using this medication must adhere to strict safety guidelines. It is contraindicated for individuals with a known hypersensitivity to letermovir or any of its components. Furthermore, it is not advisable to use this medication alongside certain drugs due to the potential for serious drug interactions. Healthcare providers recommend caution for pregnant or breastfeeding women, individuals with liver issues, and those who consume alcohol.
Anvimo 240mg Tablet is FDA-approved for the prevention of cytomegalovirus (CMV) infection in adult patients who:
This medication is used prophylactically and should not be used to treat an active CMV infection.
Anvimo 240mg Tablet functions by blocking the CMV DNA terminase complex, a key component required for viral replication. Unlike conventional antiviral drugs that target DNA polymerase, this medication disrupts viral DNA processing and packaging, ultimately preventing the virus from multiplying and spreading in the body.
By stopping CMV replication early in the process, this drug significantly lowers the risk of CMV disease in transplant recipients. The unique mechanism of action makes it highly effective while reducing the likelihood of cross-resistance seen with other CMV treatments. Due to its targeted action, it is well tolerated with a lower risk of severe toxicity compared to older antiviral medications.
Serious drug interactions can alter the effectiveness of Anvimo 240mg Tablet or increase the risk of side effects. Patients should inform their doctor about all medications, including herbal and over-the-counter drugs, before starting this medication.
Notable Drug Interactions:
The usual recommended dosage of Anvimo 240mg Tablet for CMV prophylaxis is once daily. However, if taken in combination with cyclosporine, the dose is reduced to 240 mg daily to prevent excessive drug levels. This medication is available in oral tablets and intravenous (IV) infusion forms. Oral tablets should be swallowed whole with or without food, while the IV infusion must be administered under medical supervision to ensure proper dosing and monitoring.
Anvimo 240mg contains Letermovir, an antiviral agent used to prevent cytomegalovirus (CMV) infection in patients who have undergone allogeneic hematopoietic stem cell transplantation (HSCT) and are CMV-seropositive
Common Side Effects:
Serious Side Effects:
Molecule Name: Letermovir
Therapeutic Class: CMV DNA terminase inhibitor
Pharmacological Class: Antiviral agent
Indications:
Prevention of CMV infection in HSCT patients
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