Sale!

AZIMBRA

Name: AZIMBRA
Brand: ABBOT INDIA LIMITED
SKU: 361
Availability: InStock

ADALIMUMAB INJECTION 40MG

2-8* C

MRP	:	~~MRP ₹21,825.00~~
Price	:	₹9,000.00
You Save	:	₹12,825.00 (58.76%)

1 prefilled syringe(s)

SKU: 361 Category: Rheumatology Tags: COLD CHAIN, Rheumatology Brand: ABBOT INDIA LIMITED

Azimbra 40mg Injection, an antirheumatic agent containing the active compound Adalimumab, belongs to the class of medications known as TNF (tumor necrosis factor) inhibitors. It is utilized to manage the symptoms of various autoimmune diseases, either as a standalone therapy or in conjunction with other drugs.

However, there are important contraindications and precautions associated with its use. Azimbra 40mg Injection is not recommended if you have an allergy to Adalimumab or any other ingredients in the medicine. It is also advised against if you are suffering from severe infections, such as tuberculosis or sepsis, or any other significant infection, or if you have a compromised immune system. Patients with moderate or severe heart failure should also avoid this medication. Before initiating any treatment with Azimbra 40mg Injection, it is crucial to inform your doctor if you have any active infection, or any pre-existing heart, liver, or renal issues. Children aged six or below should consult their doctor before using Azimbra 40mg Injection. Geriatric patients over 65 years old are more susceptible to infections while on this medication, thus close monitoring for side effects is essential. It is also advised to ensure your child has an up-to-date vaccination schedule to minimize the risk of developing infections.

The decision to use Azimbra 40mg Injection during pregnancy and breastfeeding will be made by your doctor only if it is deemed absolutely necessary, as there is a potential risk of infections to the child. Women of reproductive age are recommended to use effective contraceptive methods throughout the therapy and for at least five months after its completion. You should inform your doctor if you are pregnant or planning to get pregnant to discuss appropriate contraceptive methods. Furthermore, it is essential to disclose all medicines, over-the-counter drugs, vitamin, and herbal supplements you are currently taking to your physician before commencing therapy. Patients receiving Azimbra 40mg Injection should be closely monitored by their healthcare provider for any signs of side effects.

Rheumatoid arthritis
Polyarticular juvenile idiopathic arthritis
Enthesitis-related arthritis
Ankylosing spondylitis
Axial spondyloarthritis without radiographic evidence of ankylosing spondylitis
Psoriatic arthritis
Plaque psoriasis
Hidradenitis suppurativa
Crohn’s disease
Ulcerative colitis
Non-infectious uveitis

Azimbra 40mg Injection, containing Adalimumab, functions as a potent antirheumatic agent by directly targeting and inhibiting Tumor Necrosis Factor-alpha (TNF-alpha). TNF-alpha is a key pro-inflammatory cytokine that plays a central role in the body's immune and inflammatory responses. In autoimmune diseases, an excessive or dysregulated production of TNF-alpha leads to chronic inflammation and tissue damage. Azimbra 40mg Injection works by specifically binding to TNF-alpha, effectively preventing this cytokine from attaching to its corresponding receptors on cell surfaces. By blocking this crucial interaction, Azimbra 40mg Injection restricts TNF-alpha's ability to mediate downstream signaling pathways. These signaling pathways are fundamental regulators of the inflammatory response, influencing processes such as the activation of immune cells, the generation of other inflammatory cytokines, and the recruitment of inflammatory cells to sites of inflammation. Consequently, by disrupting this critical signaling cascade, Azimbra 40mg Injection significantly decreases inflammation in various autoimmune diseases, leading to a reduction in symptoms like pain, swelling, and redness, and helping to slow disease progression.

It is critically important to provide your healthcare provider with a comprehensive list of all medications you are currently taking or have taken recently. This includes not only prescription medications but also over-the-counter drugs, nutritional or vitamin supplements, and all herbal products. The reason for this thorough disclosure is that certain medications can interact with Azimbra 40mg Injection. Such interactions could potentially reduce the effectiveness of Azimbra 40mg Injection or lead to undesirable side effects, which could compromise your treatment and well-being. Furthermore, it is imperative to note that live vaccines must not be used concurrently with Azimbra 40mg Injection due to the immunosuppressive nature of the latter, which could lead to vaccine-related complications. Your healthcare provider needs this information to identify and manage any potential interactions and ensure your safety and the optimal efficacy of your treatment.

Azimbra 40mg Injection is administered via subcutaneous injection, meaning it is given under the skin. The specific dosage and frequency of Azimbra 40mg Injection will be determined by various individual factors, including the patient's age, body weight, overall health status, and the particular type and stage of the autoimmune disease being treated. It is absolutely crucial to adhere strictly to the dosing instructions provided by your healthcare provider and never to adjust the dosage or frequency without prior consultation with them. While a doctor or another healthcare professional will provide comprehensive training on how to use this injection, it is imperative that you do not attempt to self-administer this injection until you have received adequate training.

If a dose is missed, it should be administered as soon as you remember, unless it is within six hours of your next scheduled dose. In such a scenario, the missed dose should be skipped entirely, and you should resume your regular dosing schedule with the next planned injection. It is very important not to take a double dose of Azimbra 40mg Injection to compensate for a missed dose.

Store in a refrigerator (2°C – 8°C).
Do not freeze.
Protect the medicine from light and excessive moisture.
Keep the medicine out of reach of children and pets
It is important to get the dose at the scheduled time. If you missed the schedule, contact your doctor and reschedule the dose.

Serious

Heart problems
Abnormal heart beat
Severe skin reactions
GI bleeding
Abnormal blood count values
Liver injury
Bone problems
Infections
Severe respiratory problems

Common:

Injection site reactions
Rash
Headache
Sinusitis
Upper respiratory infections
Fever

Breast Feeding

Consult Your Doctor

The mother's clinical requirement for Azimbra 40mg Injection and any potential negative effects on the breastfed infant are compared and your physician will prescribe only if the benefits outweigh the risks. Your physician will prescribe it only if necessary on an individual case to case basis.

Alcohol

Unsafe

Azimbra 40mg Injection is metabolized in the liver, and excessive alcohol consumption can also lead to liver damage. The use of two concomitantly may potentially increase the risk of liver problems.

Liver

Consult Your Doctor

Azimbra 40mg Injection should be taken cautiously in patients with liver problems. Inform your physician if you have any liver diseases before initiating the treatment.

Lungs

Consult Your Doctor

Azimbra 40mg Injection should be used with caution in individuals who have respiratory issues. Let your doctor know if you have any lung conditions before starting any treatment.

Driving

Consult Your Doctor

Azimbra 40mg Injection may somewhat impair your ability to operate machinery, ride a bike, or drive. After taking this medication, a spinning sensation in the room and blurred vision are expected.If a patient experiences any side effects that affect their ability to drive or operate machinery safely while taking Azimbra 40mg Injection, they should avoid these activities and seek medical advice.

Pregnancy

Consult Your Doctor

Azimbra 40mg Injection should not be taken while pregnant unless prescribed by a physician. Your physician will prescribe it only if necessary on an individual case to case basis. Inform your physician if you are pregnant, suspecting, or planning to get pregnant during the treatment. Use effective contraception during the treatment and for at least 5 months after the last dose.