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1 vial(s)
Denosurel 120mg Injection contains Denosumab, a monoclonal antibody that helps manage bone-related complications. It is primarily prescribed for conditions involving bone loss, such as osteoporosis, particularly in postmenopausal women, and to prevent skeletal complications in patients with cancers like multiple myeloma or bone metastases. The medication works by targeting and inhibiting the RANK ligand—a protein essential for the development and activation of osteoclasts, the cells responsible for bone resorption. By blocking this protein, Denosurel slows down bone breakdown, enhances bone density, and reduces the likelihood of fractures.
Its use requires careful clinical judgment, especially in patients with renal impairment, where kidney function should be regularly monitored. The medication is not suitable for children or adolescents, as safety and efficacy in these groups have not been established. Individuals with a known allergy to Denosumab or any of the components in the injection should avoid its use. Likewise, those with existing hypoparathyroidism must be treated with caution, as the drug’s impact on calcium metabolism could worsen their condition.
Throughout the treatment, it is critical to ensure adequate levels of calcium and vitamin D to support healthy bone maintenance and avoid hypocalcemia, a possible side effect.
Denosurel 120mg Injection is used in the treatment of the following condition:
Denosurel 120mg Injection delivers significant therapeutic benefits by directly addressing the underlying mechanisms of bone loss. Its primary action involves inhibiting the RANK ligand, a key protein that stimulates the formation and activity of osteoclasts—the cells responsible for breaking down bone tissue. By blocking this pathway, Denosurel effectively slows bone resorption.
As a result, the medication not only helps preserve existing bone mass but also promotes an increase in bone mineral density (BMD), a crucial indicator of bone strength and resistance to fractures. This is especially beneficial for individuals with osteoporosis or those with cancer-related bone degradation, where bone fragility is a serious concern.
The improvement in BMD and the reduced risk of fractures translate into better mobility, less pain, and a significantly lower likelihood of experiencing serious bone injuries. These outcomes contribute to enhanced overall bone health and a meaningful improvement in the patient's quality of life—allowing for greater independence and reduced reliance on pain management or surgical intervention
It is important to inform your doctor about all the medications you are currently taking or have recently taken, including prescription drugs, over-the-counter medications, herbal remedies, and dietary or vitamin supplements. Some of these substances may interact with Denosurel 120mg Injection, potentially reducing its effectiveness or increasing the risk of unwanted side effects.
These interactions can interfere with how Denosumab works in your body or how your other medications are metabolized. Your doctor needs a complete picture of your current treatments to make informed decisions and adjust your medication plan if necessary. Full disclosure helps ensure your safety and the optimal effectiveness of your therapy.
Denosurel 120mg Injection is administered by a qualified healthcare professional, typically in a clinical or hospital setting. It is given as a subcutaneous injection, meaning it is injected under the skin—commonly in the upper arm, upper thigh, or abdomen. The dosage and frequency of administration are determined by the prescribing physician based on the patient’s medical condition, severity of disease, overall health status, and response to previous treatments.
It is crucial not to self-administer this injection unless specifically instructed and trained by a healthcare provider. Adherence to the prescribed schedule and dosage is essential for the medication to be effective and to minimize the risk of complications or adverse effects. Regular follow-up and lab monitoring may also be necessary during treatment to assess progress and ensure safety.
Serious:
Common:
Whether Denosurel 120mg Injection is excreted in milk is unknown. So it is better to consult a healthcare provider if you are a breastfeeding mother before taking this medication.
It is generally recommended to avoid or limit alcohol consumption while taking Denosurel 120mg Injection. Alcohol can interact with this medication, potentially increasing the risk of side effects.
Denosurel 120mg Injection is primarily metabolized in the liver, and its safety has not been extensively studied in individuals with severe liver impairment. It is crucial to communicate any pre-existing liver conditions or changes in liver function to your healthcare provider to ensure this medication's safe and effective use.
If you have a lung or respiratory disorders history, it is important to consult your healthcare provider before taking Denosurel 120mg Injection.
Patients receiving Denosurel 120mg Injection should be advised to avoid driving or operating machinery if they experience side effects such as fatigue, dizziness, or blurred vision, impairing a patient's ability to drive or operate machinery safely.
The safety of using Denosurel 120mg Injection during pregnancy has not been established. Limited studies are available regarding the use of this medication in pregnant women, so it is recommended to use caution and consult a doctor before considering its use during pregnancy.
Molecule Name: Denosumab
Therapeutic Class: Anti-resorptive agent
Pharmacological Class: Monoclonal Antibodies
Indications:
1. Osteoporosis
2. Bone loss due to hormonal therapy in breast or prostate cancer
3. Multiple myeloma
4. Bone metastases
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