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GRAFEEL VIAL

Name: GRAFEEL VIAL
Brand: DR REDDY'S LABORATORIES LTD
SKU: 338
Availability: InStock

FILGRASTIM INJECTION 300MCG

2-8* C

MRP	:	~~MRP ₹724.31~~
Price	:	₹280.00
You Save	:	₹444.31 (61.34%)

1 vial(s) of 1ml

SKU: 338 Categories: Anti-Cancer, Anti-Cancer Drugs, CANCER Tags: ANTI CANCER, COLD CHAIN Brand: DR REDDY'S LABORATORIES LTD

Grafeel 300mcg injection contains filgrastim, a white blood cell growth factor (granulocyte-colony stimulating factor). It is an FDA-approved medication designed to mitigate the risk of febrile neutropenia (fever or infection associated with a low white blood cell count) and to shorten the duration of neutropenia (a low white blood cell count) in individuals undergoing chemotherapy for non-myeloid cancers. This injection is also utilized to boost white blood cell counts and reduce the duration of fever in patients with acute myeloid leukemia.

Furthermore, Grafeel 300mcg injection is beneficial for individuals undergoing bone marrow transplants and those with severe chronic neutropenia (a persistently low number of neutrophils in the blood). It serves to prepare the blood for leukapheresis, a medical procedure involving the removal of specific blood cells. Another significant application is to enhance the survival rate in people exposed to harmful levels of radiation, which can severely damage the bone marrow. Additionally, it is indicated for patients with advanced HIV infection to help reduce their risk of infections.

Belonging to the class of medications known as colony-stimulating factors, Grafeel 300mcg injection works by stimulating the body’s production of white blood cells. White blood cells are crucial for the body’s defense against infections. Since these cells are highly susceptible to the effects of chemotherapy, their numbers can decrease significantly, leaving the body vulnerable to bacterial infections. It is important to inform your physician if you have or have had liver disease, kidney problems, sickle cell anemia, or bone disease. Common side effects associated with this injection include fever, pain, rash, cough, shortness of breath, and nosebleeds.

To prevent infections after chemotherapy due to decreased white blood cells (neutropenia)

Grafeel 300mcg injection functions as a colony-stimulating factor that specifically targets blood-forming cells. It achieves this by binding to particular receptors found on the surface of these cells. This binding action then triggers a process that encourages the cells to divide and multiply, leading to an increase in their numbers. Furthermore, it prompts these cells into a state of functional activation, ensuring they are ready to perform their roles effectively within the body's systems.

It's really important to tell your healthcare provider about all the medicines you're taking, or have taken recently. This includes not just your prescription medications, but also anything you buy over-the-counter, like pain relievers or cold medicine, as well as any nutritional or vitamin supplements, and even herbal products.

The reason for sharing this complete list is that certain medications can interact with Grafeel 300mcg injection. These interactions might make Grafeel less effective, meaning it won't work as well to help your body produce white blood cells. They could also lead to undesirable side effects, which might impact your health and the success of your treatment. Your doctor needs all this information to identify any potential interactions and make sure your treatment plan with Grafeel 300mcg injection is as safe and effective as possible for your condition.

Grafeel 300mcg injection is conveniently available in a prefilled syringe. Its administration will be handled by a qualified healthcare professional, who will either inject it into the fatty tissues just under your skin (subcutaneously) or slowly administer it intravenously into your vein. The specific dose, the chosen route of administration, and the frequency of the injections will be determined by your doctor, taking into consideration your particular disease condition and other relevant medical factors.

Should your physician decide that you or your caregiver are suitable to administer the Grafeel 300mcg injection at home, it is crucial to carefully read the "Instructions for Use" provided in the package insert that accompanies the medicine. Furthermore, your doctor or another healthcare professional will provide thorough training on the correct self-administration procedure. It is imperative that you do not administer the medicine yourself if you have not received this training and are unsure about the administration process.

Store Grafeel 300mcg injection in a refrigerator (2°C – 8°C). Do not freeze.
Do not shake the pre-filled syringe.
Discard the medicine if stored at room temperature for more than 48 hours.
Keep it out of reach from children and pets.
It is important to get the dose at the scheduled time. If you missed the schedule, contact your doctor immediately for advice.

Common

Pain in the bones, joints, and muscles
Pain at the site of Injection
Fever
Itchiness and skin rash
Nausea
Headaches
Dizziness and tiredness
Nose bleeding
Hair fall

Serious

Inflammation of Aorta
Capillary leak syndrome (plasma leaks out of tiny blood vessels)
Hypersensitivity reactions
Changes in urine color
Swelling in hands, feet, face, and abdomen
Difficulty in breathing
Sickle cell anemia

Breast Feeding

Unsafe

It is unsafe to breastfeed during the treatment with this Grafeel 300mcg injection because it may cause harm to the baby. Please consult your doctor before breastfeeding.

Alcohol

Unsafe

It is unsafe to consume alcohol with Grafeel 300mcg injection. Please consult your doctor for more advice.

Liver

Consult Your Doctor

It is unknown whether Grafeel 300mcg injection can be administered in patients with liver disorders. Inform your physician if you have any liver problems before starting treatment with this Injection.

Lungs

Consult Your Doctor

It is unknown whether Grafeel 300mcg injection can be administered to patients with lung problems. Consult your doctor if you have any lung diseases before starting the treatment.

Driving

Unsafe

It is unsafe to travel, drive vehicles, or operate heavy machinery after taking (1 hour) Grafeel 300mcg injection. Please consult your doctor.

Pregnancy

Unsafe

Grafeel 300mcg injection is unsafe when administered during pregnancy because it may cause birth defects in your baby. Consult your doctor if you are pregnant or planning for pregnancy during the treatment.