IMATIREL 400

Imatirel tablet contains the active substance imatinib. It is an antineoplastic drug that belongs to the class tyrosine kinase inhibitor. This tablet is used in treating adults and children with chronic myeloid leukaemia (CML- it is a form of leukaemia in which certain abnormal white blood cells start growing out of control). It is also indicated to treat Philadelphia chromosome-positive acute lymphoblastic leukaemia (Ph-positive ALL). It is also used to treat certain types of gastrointestinal stromal tumours (GIST, a kind of tumour that grows in the walls of the digestive passages and may spread to other parts of the body)

Imatirel tablet is also used to treat myelodysplastic/myeloproliferative diseases (MDS/MPD). These are a group of blood diseases in which some blood cells start growing out of control. They also treat hypereosinophilic syndrome (HES) and/or chronic eosinophilic leukaemia (CEL); these are blood diseases in which some blood cells (eosinophils) start growing out of control. This medicine is also intended to treat dermatofibrosarcoma protuberans (DFSP), a cancer of the tissue beneath the skin in which some cells start growing abnormally. It works, inhibiting the growth of these abnormal blood cells.

Do not take the Imatirel tablet if you are allergic to imatinib or any other ingredients in this medicine. Before initiating the treatment, inform your physician if you have kidney, heart or liver problems, if you have thyroid problems, or if your thyroid gland has been removed. Notify your doctor if you ever had or have a hepatitis B infection because this medicine could cause the hepatitis B to become active again. Report any symptoms of bruising, bleeding, fever, fatigue and confusion when taking this medicine. This medicine may cause fertility problems.