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1 vial(s)
Leugard 22.5mg Depot Injection contains leuprolide acetate, a synthetic hormone that works by initially stimulating, and then significantly reducing, the production of certain sex hormones—testosterone in men and estrogen in women—through its action on the pituitary gland. This suppression helps slow the growth of hormone-sensitive conditions such as prostate cancer, breast cancer, endometriosis, uterine fibroids, and central precocious puberty.
At the start of treatment, you may experience a temporary surge in hormone levels, which can cause a brief worsening of symptoms. This is a known effect and typically stabilizes with continued use. Regular monitoring by your doctor is essential, especially if you have conditions like diabetes, heart disease, depression, or are at risk for bone density loss.
This injection is not suitable during pregnancy, while breastfeeding, or in patients with certain medical histories such as unexplained vaginal bleeding, seizure disorders, or past surgical removal of the testes. Use of non-hormonal contraception is recommended for women of reproductive age during treatment.
Before starting Leugard, it’s important to inform your doctor of all medications and supplements you’re taking, including prescription drugs, OTC medications, herbal products, and vitamins, as interactions could reduce the drug’s effectiveness or increase the risk of side effects.
Leugard 22.5mg Depot Injection is used in the treatment of the following:
Leugard 22.5mg Depot Injection functions by gradually desensitizing the GnRH receptors in the pituitary gland. This desensitization results in a marked reduction in the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH). As a consequence, the levels of sex hormones—estrogen in women and testosterone in men—significantly decrease.
This hormone suppression is therapeutic in a variety of hormone-dependent conditions. In men, it slows the progression of prostate cancer by depriving cancer cells of the testosterone they need to grow. In women, it helps shrink uterine fibroids, relieves the pain and inflammation associated with endometriosis, and is used to manage hormone-responsive breast cancers. In children, it delays premature puberty by halting the early hormonal changes responsible for physical development.
The clinical benefits stem from reducing hormone-driven stimulation of affected tissues, ultimately leading to symptom relief, disease control, and improved quality of life in the targeted conditions.
Before starting treatment with Leugard 22.25mg Depot Injection, it's important to inform your healthcare provider about all the medications and supplements you are currently taking or have recently taken. This includes prescription drugs, over-the-counter medicines, nutritional or vitamin supplements, herbal products, and even recent vaccinations. Some medications or substances can interact with Leugard, potentially altering its effectiveness or increasing the risk of adverse effects.
Disclosing your complete medication history allows your doctor to anticipate and manage possible interactions, adjust dosages if needed, and ensure that your treatment is both safe and effective. If you’re unsure about any product or supplement, bring it up during your consultation for clarity.
Leugard 22.5mg Depot Injection is typically administered by a healthcare professional either in the arm, thigh, or abdominal area as an intramuscular or subcutaneous injection. The injection should never be self-administered, as proper technique and site selection are crucial to ensure its effectiveness and reduce the risk of complications.
The dosage and frequency of administration will be carefully determined by your physician based on your specific medical condition, treatment goals, hormone levels, and response to therapy. Each individual may require a tailored approach, so it's essential to follow your doctor's instructions precisely and attend all scheduled follow-up appointments to monitor treatment progress and make adjustments if necessary.
Serious
Common
It is not advised to breastfeed as it is unknown whether the drug is excreted in human milk. Inform your doctor if you are breastfeeding before taking Leugard 22.25mg Depot Injection.
Consuming alcohol during the Leugard 22.25mg Depot Injection treatment may increase the risk of thinning bones and other side effects. Hence, caution should be taken. Consult your doctor for more information.
Leugard 22.25mg Depot Injection should be used cautiously in patients with liver impairment. Consult your doctor before receiving it. Notify your doctor about underlying liver conditions.
Inform your doctor if you experience any pulmonary embolism, shortness or difficulty of breath, or other underlying lung conditions. Consult your doctor for more information.
Leugard 22.25mg Depot Injection can cause drowsiness, visual disturbances, or dizziness. It is unsafe; hence, avoid driving if you are unwell.
It is unsafe to use Leugard 22.25mg Depot Injection because it is contraindicated in pregnant women as it may cause foetal harm. Tell your doctor if you are pregnant or planning to get pregnant before taking this treatment.
Molecule Name: Leuprolide acetate
Therapeutic Class: Antineoplastics
Pharmacological Class: Gonadotropin releasing hormone (GnRH) agonists
Indications:
1. Prostate cancer
2. Hormone-responsive breast cancer in perimenopausal (around menopause) women
3. Endometriosis (a painful illness in which the tissue that normally lines the inside of the uterus grows outside of your uterus)
4. Central precocious puberty in children under 10 years (a child’s body begins to change into an adult too soon caused by a release of certain hormones))
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