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MIDOSTAR 25MG

MIDOSTAURIN SOFT GELATIN

MRP	:	~~MRP ₹4,119.38~~
Price	:	₹2,500.00
You Save	:	₹1,619.38 (39.31%)

4 capsule(s) in a strip

SKU: 097 Categories: Anti-Cancer, Anti-Cancer Drugs, CANCER Tag: ANTI CANCER DRUGS Brand: Zydus Lifesciences Limited

Midostar 25mg Capsule works by blocking the action of specific enzymes known as tyrosine kinases, particularly the FLT3 receptor, which plays a crucial role in the growth and survival of certain cancer cells. In patients with acute myeloid leukemia (AML) harboring FLT3 mutations, this abnormal receptor promotes the uncontrolled production of immature white blood cells. By inhibiting FLT3, Midostar helps slow down or stop the proliferation of these leukemic cells, allowing the body to regain better control over normal blood cell production.

In the case of aggressive systemic mastocytosis (ASM) and related mast cell disorders, Midostar inhibits other tyrosine kinases like KIT D816V, which are responsible for the abnormal growth and accumulation of mast cells in various tissues. By targeting these kinases, Midostar reduces the number of mast cells and alleviates symptoms caused by their excessive activity, such as inflammation, organ damage, and systemic reactions.

This dual mechanism makes Midostar a targeted therapy aimed at interrupting the growth signals in specific blood and mast cell cancers, improving patient outcomes when used under the guidance of an oncologist or hematologist.

Midostar 25mg Capsule is used in the treatment of the following:

Acute myeloid leukemia (AML)
Aggressive systemic mastocytosis (ASM)
Systemic mastocytosis with associated hematological neoplasm (SM-AHN)
Mast cell leukemia (MCL)

Midostar 25mg capsule is a kinase inhibitor that effectively blocks the activity of several receptor tyrosine kinases. Its primary action targets abnormal cells that express mutations in the FLT3 gene, a mutation commonly found in acute myeloid leukemia (AML). By inhibiting these mutant kinases, Midostar interferes with the signaling pathways that drive the excessive growth and division of these cancerous cells. As a result, it slows down or halts the proliferation of the abnormal cells, helping to restore a more balanced production of healthy blood cells and supporting the effectiveness of accompanying chemotherapy treatments.

It is essential to inform your healthcare provider about all the medications you are currently using, including prescription drugs, over-the-counter treatments, recent or scheduled vaccinations, nutritional supplements, vitamins, and any herbal or traditional remedies. Some of these substances may interact with Midostar 25mg capsule, either by diminishing its therapeutic effects or increasing the risk of adverse reactions. These interactions can potentially alter how Midostar is absorbed, metabolized, or eliminated from the body. To ensure safe and effective treatment, your doctor will assess all potential interactions and may adjust your medication regimen accordingly. Always consult your physician before starting or stopping any medication while on Midostar therapy.

Your doctor will determine the appropriate dose and duration of Midostar 25mg capsule treatment based on your specific medical condition, the severity of the disease, your response to therapy, and other individual factors such as age, weight, and overall health. It is crucial to follow the prescribed dosage instructions exactly as advised. Take Midostar 25mg capsule orally with food, ideally at the same time each day, to maintain a consistent level of the medication in your body. Swallow the capsule whole with a glass of water; do not open, crush, break, or chew it, as this may affect how the medication is absorbed and could increase the risk of side effects. Adhering strictly to your doctor’s instructions will help ensure the maximum benefit from the treatment.

Store Midostar 25mg capsule at room temperature (25°C)
keep the capsule away from the reach of children and pets.
If you miss a dosage, take it as soon as you remember. If it is almost time for the next dose, skip the missing dose.
Do not take a double dose to compensate for a missed dose.

Common side effects of Midostar 25mg Capsule are:

Swelling in the lower limbs
Skin rash
Increased blood sugar levels
Abdominal pain
Constipation, diarrhoea
Nausea, vomiting
Musculoskeletal pain
Headache
Bleeding from nose
Upper respiratory infection
Tiredness
Fever

Serious side effects of Midostar 25mg Capsule are:

Heart failure
GI bleeding
Fever with decreased blood cell counts
Hypersensitivity reactions
Kidney problems
Pneumonia
Blood infection

Breast Feeding

Unsafe

Breastfeeding is not recommended in patients taking Midostar 25mg capsule because the medicine passes into the breast milk in small amounts and may harm the baby.

Alcohol

Unsafe

It is unsafe to consume alcohol when taking Midostar 25mg capsule because it may cause alcohol-related problems, epilepsy, or liver problems.

Liver

Unsafe

Midostar 25mg capsule should be cautiously administered in patients with severe liver diseases. Dose adjustments are necessary for severe liver failure. Inform your physician if you have liver problems before initiating the therapy.

Lungs

Consult Your Doctor

It is unknown whether Midostar 25mg capsule can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.

Driving

Unsafe

Driving vehicles or operating machinery after taking Midostar 25mg capsule is unsafe as you may develop dizziness and vertigo.

Pregnancy

Unsafe

Midostar 25mg capsule is unsafe to administer in pregnant women because it may cause birth defects. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant. Using effective contraception during the treatment and for at least 4 months after your last dose is necessary.