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REDITUX 100

Name: REDITUX 100
Brand: DR REDDY'S LABORATORIES LTD
SKU: 346
Availability: InStock

RITUXIMAB INJECTION 100MG/10ML

2-8* C

MRP	:	~~MRP ₹8,137.57~~
Price	:	₹2,800.00
You Save	:	₹5,337.57 (65.59%)

1 vial(s) of 10ml

SKU: 346 Category: Rheumatology Tags: COLD CHAIN, Rheumatology Brand: DR REDDY'S LABORATORIES LTD

Reditux 100mg injection, containing the active constituent rituximab, is used to treat a variety of conditions in adults. It is administered alone or in combination with other medications for non-Hodgkin’s lymphoma (a cancer affecting B-lymphocytes) and chronic lymphocytic leukemia (a common B-cell cancer). It is also indicated for moderate-to-severe rheumatoid arthritis, used in conjunction with methotrexate. Additionally, Reditux 100mg treats granulomatosis with polyangiitis or microscopic polyangiitis (blood vessel inflammation primarily affecting lungs and kidneys) in adults and children aged 2 years and older. Another application is in the treatment of moderate to severe pemphigus vulgaris, an autoimmune condition leading to painful blisters on the skin and mucous membranes.

Reditux 100mg injection belongs to the class of anti-CD20 monoclonal antibodies. It should not be used if you are allergic to rituximab or any other ingredients, have a weakened immune system, or are experiencing any severe active infection. Before starting treatment, inform your physician about any history of heart disease, heart failure, or breathing problems. It’s crucial to discuss any past hepatitis B infection with your doctor, as the infection may reactivate in some cases, potentially severely. Pregnancy and breastfeeding are not recommended during and after treatment with this injection.

Common side effects of Reditux 100mg injection include blood infections, reduced red blood cells, dizziness, facial and body swelling, itchy skin, diarrhea, increased sweating, and fluctuations in blood pressure. If you are able to become pregnant, use effective contraceptives during treatment and for 12 months after the last dose. This medicine can cause severe infusion reactions during or within 24 hours of administration. You must inform your physician or healthcare professional immediately if you experience any infusion reactions, such as increased blood pressure, chest pain, headache, breathing difficulties, vomiting, skin rashes, or throat swelling.

Non-hodgkin’s lymphoma (NHL)
Chronic lymphocytic leukemia (CLL)
Rheumatoid Arthritis
Granulomatosis with polyangiitis or microscopic polyangiitis
Pemphigus vulgaris

Reditux 100mg injection, which contains rituximab, is a monoclonal antibody specifically designed to target the CD20 antigen. This antigen is a protein found on the surface of B-lymphocytes, a type of white blood cell that plays a crucial role in the immune system.

In the context of Non-Hodgkin's Lymphoma (NHL) and Chronic Lymphocytic Leukemia (CLL), rituximab's mechanism involves binding to these CD20 proteins on cancerous B-cells. This binding action initiates several pathways that collectively lead to cell death. It effectively blocks the activation and growth signals that these cancer cells rely on, thereby producing its anticancer effects.

For rheumatoid arthritis, an autoimmune disease, rituximab's action is also linked to its effect on B-cells. Although the precise mechanism is not fully understood, it is believed that by depleting CD20-positive B-cells, Reditux 100mg injection helps to reduce the inflammatory processes central to rheumatoid arthritis. This involves inhibiting the production of rheumatoid factor, a type of autoantibody, and reducing antigen presentation by B-cells, which in turn dampens T-cell activation and the production of pro-inflammatory cytokines. This overall suppression of specific immune responses contributes to the therapeutic benefits observed in rheumatoid arthritis.

It is critically important to provide your healthcare provider with a comprehensive list of all medications you are currently taking or have taken recently. This includes not only prescription medications but also over-the-counter drugs, nutritional and vitamin supplements, and all herbal products. In particular, you must inform your doctor if you are taking any medicines for blood pressure or other heart conditions. The reason for this thorough disclosure is that certain medications can interact with Reditux 100mg injection. Such interactions could potentially reduce the effectiveness of Reditux 100mg injection or lead to undesirable side effects, which could compromise your treatment and well-being. Your healthcare provider needs this information to identify and manage any potential interactions, thereby ensuring the safest and most effective use of Reditux 100mg injection for your condition.

Reditux 100mg injection must only be administered by a trained doctor or nurse; self-administration is strictly prohibited. Before receiving Reditux 100mg injection, you will be given other medications (known as pre-medication) to help reduce the likelihood of experiencing possible side effects. Your doctor will determine the appropriate dose and duration of your treatment, taking into account the severity of your disease and other individual factors. This medication will be administered as an intravenous infusion, meaning it will be given directly into your vein. Throughout the infusion, you will be carefully monitored for any unwanted side effects.

Store Reditux 100mg injection in the refrigerator (2°C to 8°C)
Do not freeze
keep the injection away from the reach of children and pets.
If you have missed any dosing appointments, inform your doctor and schedule immediately.

Swelling in the face and body
Diarrhea and nausea
Itchy skin
Anemia
Muscle spasm
Headache
Urinary tract infection
Fever, chills, and shivering
Inflammation of nasal cavities
Cough, sore throat
Loss of hair

Serious

Increased or decreased blood pressure
Chest pain
Hypersensitivity reactions
Hepatitis B viral infection
Memory loss, trouble thinking, difficulty in walking

Breast Feeding

Unsafe

Breastfeeding is not recommended in patients taking Reditux 100mg injection because the medicine passes into the breast milk in small amounts and may harm your baby.

Alcohol

Unsafe

Consuming alcohol may affect the effectiveness of Reditux 100mg injection. Stop consuming alcohol if you are taking this medicine.

Liver

Consult Your Doctor

Whether Reditux 100mg injection can be used in patients with liver impairment is unknown. Consult your doctor if you have or ever had liver disease or hepatitis B infection before starting the treatment. The reactivation of hepatitis viral infection can cause severe liver problems.

Lungs

Consult Your Doctor

It is unknown whether Reditux 100mg injection can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.

Driving

Unsafe

Caution is required while driving and operating machinery when you take Reditux 100mg injection because it may cause dizziness, sleepiness, tiredness, and risk of falling.

Pregnancy

Unsafe

Reditux 100mg injection is unsafe to administer in pregnant women because it may affect the fetus. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant. Using an effective birth control method during the treatment and for 12 months after your last dose is necessary.