Xpreza 300 mg Tablet is classified as an anti-cancer medication known as a demethylation agent, intended for the ongoing treatment of acute myeloid leukaemia in adults who have shown improvement after chemotherapy but were unable to finish intensive curative therapy. Acute myeloid leukaemia is a cancer that originates in the blood-forming cells of the bone marrow.
Xpreza 300 mg Tablet contains Azacitidine, which functions by disrupting the growth of cancer cells, leading to their eventual destruction by the body. It aids the bone marrow in producing normal blood cells while eliminating abnormal cells present in the bone marrow.
Occasionally, Xpreza 300 mg Tablet may lead to side effects such as nausea, vomiting, diarrhoea, constipation, fatigue, and abdominal pain. Most of these side effects typically do not necessitate medical intervention and tend to resolve on their own over time. Do not hesitate to consult your doctor if any side effects persist or worsen.
Avoid using Xpreza 300 mg Tablet if you are pregnant or breastfeeding. Seek medical advice immediately if you become pregnant while undergoing treatment with Xpreza 300 mg Tablet. This medication is not advised for children, as its safety and effectiveness have not been established. Inform your doctor about your health status and any medications you are taking to prevent potential side effects or interactions.
Xpreza 300 mg Tablet is indicated for the management of Acute Myeloid Leukaemia. The specific applications of Xpreza 300 mg Tablet include the following:
Myelodysplastic Syndrome (MDS): Xpreza 300 mg Tablet is utilized to address all forms of MDS, which is a collection of disorders characterized by the bone marrow's production of poorly formed or dysfunctional blood cells, resulting in anaemia, infections, or bleeding.
Acute Myeloid Leukemia (AML): Xpreza 300 mg Tablet is prescribed for patients with AML who are not candidates for stem cell transplantation. It aids in decreasing the quantity of abnormal blood cells while encouraging the generation of healthy ones.
Xpreza 300 mg tablet binds to RNA and DNA, interrupts their activity in actively multiplying cells, and exhibits a toxic effect on cancer cells.
Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional and vitamin supplements, and herbal products you take or have taken before the treatment. Certain medications may interact with Xpreza 300 mg tablet and cause undesirable side effects.
Xpreza 300 mg Tablet can be taken with or without food, as food does not affect its absorption or effectiveness.
Xpreza 300 mg Tablet is usually taken once daily; however, follow your doctor's advice regarding the dosage and duration.
Swallow the tablet as a whole with a glass of water.
Do not break, crush or chew Xpreza 300 mg Tablet .
• Store in a cool and dry place away from sunlight.• Keep Xpreza 300 mg Tablet out of reach and sight of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Serious:
Drowsiness
Shivering
Jaundice
Stomach bloating
Unusual bleeding or bruising
Reduced urination
Increased thirst
Dizziness
Confusion
Chest pain
Breathlessness
Allergies
Common:
Disturbances in the blood count (RBC, WBC, Platelets)
Nausea, vomiting, diarrhea
Constipation
Tiredness
Skin reactions like redness and pain at the site of the tablet
Decreased appetite
Dizziness
Pain in extremities
Joint pain
Stomach pain
Headache
Sore nose and throat
Rashes and bruising
Avoid using Xpreza 300 mg Tablet if you have an allergy to any of its ingredients or if you are currently breastfeeding.
Notify your doctor if you have any liver or kidney issues.
Seek immediate medical help if you notice signs of neutropenia, such as fever or chills, extreme fatigue, body aches, or an unusual headache, or if you experience symptoms of thrombocytopenia, including unexpected bleeding or bruising.
Consult your physician if you are pregnant, intend to become pregnant, or if you are planning to father a child.
Fact Box of XPREZA 300MG
Molecule Name: Azacitidine
Therapeutic Class: Anti-metabolites
Pharmacological Class: Anti-Neoplastics
Indications:
1. Treat advanced or metastatic non-small lung cancer (NSCLC),
2. To Treat Advanced or metastatic pancreatic cancer.
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