Adfill 6mg Injection contains Pegfilgrastim as its active ingredient. This medication falls under the category of granulocyte colony-stimulating factors and has been approved by the FDA to reduce the risk of febrile neutropenia (the occurrence of fever or infection due to low white blood cell count) and to shorten the duration of neutropenia (a low white blood cell count) in patients undergoing bone marrow suppressive chemotherapy. Additionally, it is indicated to enhance survival rates in individuals exposed to radiation therapy, which can lead to severe and life-threatening damage to the bone marrow. The drug works on blood-forming cells, promoting cell multiplication and activating cell functions.
Pegfilgrastim is a protein produced through biotechnology using E. coli bacteria. It is part of the cytokine family of proteins and closely resembles a natural protein (granulocyte-colony stimulating factor) that your body produces. White blood cells (WBC) play a crucial role in helping your body fight infections. These cells are particularly vulnerable to the effects of chemotherapy, which can lead to a reduction in their numbers. A decrease in WBC can leave your body with insufficient cells to fend off bacteria, increasing your risk of infection.
Before beginning treatment with this Injection, inform your physician if you have or have ever had liver disease, fever or infection, kidney issues, heart problems, or a family history of kidney diseases. Avoid using this Injection if you are allergic to pegfilgrastim, filgrastim, or any other components of this Injection. Report any symptoms such as left upper abdominal pain, shoulder pain, or respiratory issues to your doctor immediately. The most frequently reported side effects of Adfill 6mg Injection include pain in the bones, arms, and legs.
Adfill 6mg is a prescription Injection, and it is used to treat
Decrease the chance of infection caused by low levels of white blood cells in patients with certain types of cancer (non-myeloid) receiving bonemarrow suppressing anti-cancer drugs.
To increase the survival rate in patients receiving radiation therapy that suppresses bone marrow activity.
Follow your doctor’s instructions on the dosage and timing of this medication.
Adfill Injection may be administered by your doctor, or you may be told to inject the medication yourself at home. Your doctor will train you on how to use Adfill Injection at home.
Check the label for directions and use it as advised by the doctor.
Adfill Injection should be administered subcutaneously (under the skin) in the thighs, abdomen, buttocks, or upper arm.
Rotate the injection site each time.
Do not inject into the areas where the skin is tender, red, bruised, hard, scarred, or has stretch marks.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.
Follow your doctor’s instructions on the dosage and timing of this medication.
Adfill Injection may be administered by your doctor, or you may be told to inject the medication yourself at home. Your doctor will train you on how to use Adfill Injection at home.
Check the label for directions and use it as advised by the doctor.
Adfill Injection should be administered subcutaneously (under the skin) in the thighs, abdomen, buttocks, or upper arm.
Rotate the injection site each time.
Do not inject into the areas where the skin is tender, red, bruised, hard, scarred, or has stretch marks.
• Store in a cool and dry place away from sunlight.
• Keep Adfill Injection out of sight and reach of children.
• Cold chain - To be stored in cold places at 2ºC to 8ºC
Side effects are unwanted symptoms caused by Injections. Even though all drugs cause side effects, not everyone gets them.
Common
Pain in the bones, joints and muscles
Pain at the site of Injection
Itchiness and skin rash
Nausea
Headaches
Dizziness and tiredness
Serious
Inflammation of Aorta
Capillary leak syndrome (plasma leaks out of tiny blood vessels)
Hypersensitivity reactions
Changes in urine color
Swelling in hands, feet, face, and abdomen
Difficulty in breathing
Sickle cell anemia
Do not use Adfill Injection without the doctor's advice if you had a skin reaction or irritation to any medicine. Consult your doctor before using Adfill Injection if you are pregnant or breastfeeding. Let your doctor know if you are suffering from renal dysfunction, blood cancer, leucocytosis (high white blood cell count). Keep your doctor informed about your medical condition and all the medicines you are taking to rule out any side effects. Regular blood tests will be taken to monitor the number of white blood cells in the body. Adfill Injection is a cold chain medicine, and so it has to be stored in the refrigerator between 2-8 degrees Celsius else its efficacy might get lost.
Fact Box of ADFILL
Molecule Name: Pegfilgrastim
Therapeutic Class: Hematopoietic
Pharmacological Class: colony-stimulating factors
Indications:
Febrile neutropenia
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