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Bortlieva 2mg

BORTEZOMIB 2MG

MRP	:	~~MRP ₹5,522.81~~
Price	:	₹1,000.00
You Save	:	₹4,522.81 (81.89%)

1 Vial(s)

SKU: 1349 Categories: Anti-Cancer, Anti-Cancer Drugs Tag: ANTI CANCER DRUGS Brand: Allieva Pharma Pvt. Ltd.

Bortlieva 2mg Injection is a chemotherapeutic drug classified as a Proteasome inhibitor. It contains the active ingredient BORTEZOMIB and is utilized for treating multiple myeloma and mantle cell lymphoma. This medication is often administered alongside other chemotherapy agents such as pegylated liposomal doxorubicin, rituximab, cyclophosphamide, doxorubicin, dexamethasone, prednisolone, or thalidomide for patients who have not yet begun treatment or are not suitable for blood stem cell transplant therapy.

It is advised against using Bortlieva 2mg Injection if you have allergies to the active substances or any other components of this medication. Additionally, it is not recommended for individuals with a weakened immune system. If you are experiencing an active infection, please inform your doctor prior to starting any treatment. This medication is also not suitable for children and adolescents, nor for patients with hepatitis. Make sure to notify your healthcare provider if you have gastrointestinal issues, liver disorders, low platelet counts (thrombocytopenia), low white blood cell counts (neutropenia), tumor lysis syndrome (a metabolic complication that can arise during cancer treatment), nerve dysfunction (neuropathy), heart conditions, severe respiratory issues, pulmonary disorders, or posterior reversible encephalopathy syndrome before commencing treatment with this drug. Regular monitoring of blood counts and liver enzymes is recommended throughout the treatment duration.

The administration of Bortlieva 2mg Injection during pregnancy and breastfeeding is not advised and will only be considered by the physician if absolutely necessary, as it may pose risks to the developing fetus. It is recommended to employ effective contraceptive measures during treatment and for three months following its completion. Inform your doctor if you are pregnant or planning to conceive to discuss appropriate contraceptive options. It is essential to keep your physician informed about any relevant medical history.

Treatment of multiple myeloma
Treatment of mantle cell lymphoma

Bortlieva 2mg Injection functions by inducing a toxic effect on cancer cells. It inhibits the 26S proteasome and obstructs a key cell signaling pathway. This blockage of the signaling pathway renders the cancer cells more susceptible to chemotherapy. By inhibiting the proteasome, Bortlieva 2mg Injection interferes with the regular process of protein degradation within the cell. Consequently, this results in the accumulation of misfolded or damaged proteins, which are harmful to the cell.

The buildup of misfolded proteins initiates a cascade of cellular responses, including the activation of stress pathways and the triggering of apoptosis. Additionally, this medication promotes the accumulation of a specific protein and reduces the growth and proliferation of cancer cells.

Notify your healthcare provider of all medications you are currently taking, which includes prescription drugs, over-the-counter medications, nutritional or vitamin supplements, and herbal products.

Some medications may interact with Bortlieva 2mg Injection, potentially diminishing its effectiveness and leading to unwanted side effects.

Bortlieva 2mg Injection is delivered via intravenous injection into your vein or subcutaneously beneath the skin. This procedure is performed by a healthcare professional in a hospital environment.

The dosage and frequency of Bortlieva 2mg Injection are determined by several factors, such as the patient's age, weight, overall health, and the specific type and stage of the disease being treated. It is crucial to adhere to the dosing instructions given by a healthcare provider and to avoid altering the dosage or frequency without prior consultation. Self-administration of this injection is not permitted.

If a dose is missed, it should be taken at the earliest opportunity unless it is within 6 hours of the next scheduled dose. In such cases, the missed dose should be omitted, and the regular dosing schedule should continue. It is essential not to take a double dose of Bortlieva 2mg Injection to compensate for a missed dose.

Store in a refrigerator (2°C – 8°C).

Serious:

Peripheral neuropathy
Hypotension
Cardiac toxicity
Posterior Reversible Encephalopathy Syndrome (PRES)
Tumor Lysis Syndrome
Hepatic Toxicity
Thrombotic Microangiopathy

Common:

Loss of appetite
Sensitivity, tingling and burning sensation of the skin
Nausea, vomiting, and diarrhea
Mouth ulcers
Constipation
Muscle and bone pain
Hair loss
Fever
Reduction in blood cell count
Reduced kidney function
Shivering
Infections
Dehydration
Stomach problems
Difficulty sleeping, anxiety, mood swings, depressed mood

If you have been prescribed Bortlieva 2mg Injection, it is crucial to adhere to the guidelines given by your healthcare provider and to promptly report any side effects or concerns. Even if you start feeling better or notice a change in your symptoms, it is essential to consult your doctor before discontinuing Bortlieva 2mg Injection. Both men and women are advised to use an effective method of contraception during treatment and for three months afterward. Treatment with Bortlieva 2mg Injection may commonly lead to a reduction in the levels of red and white blood cells, as well as platelets in your blood. Consequently, you will need to undergo regular blood tests before and during your treatment with Bortlieva 2mg Injection to monitor your blood cell counts consistently. Incorporate anti-inflammatory foods into your diet, such as olive oil, nuts, seeds, fruits, vegetables, and fatty fish. Foods like avocados, almonds, seeds, and olive oil should be included in your diet as sources of healthy fats. These fats can enhance overall health by reducing inflammation. To maintain hydration, drink plenty of water throughout the day. Regularly monitor your blood sugar levels if you are on antidiabetic medication and inform your physician of any fluctuations in your blood sugar levels.

Before receiving any vaccinations, consult your physician, as some can cause illness and should not be given while you are on this medication. If you currently have or have ever had hepatitis B, inform your doctor.

Make sure to attend all scheduled appointments and follow-up visits with your healthcare provider to ensure the effectiveness of your treatment and to manage any side effects appropriately.

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