Humimab HC 40mg Injection is an antirheumatic medication that falls under the category of TNF (tumour necrosis factor) inhibitors. The active ingredient in this injection is Adalimumab. It is utilized to alleviate the symptoms of various autoimmune disorders, either alone or in conjunction with other medications.
Humimab HC 40mg Injection should not be administered if you have an allergy to its active components or any other ingredients present in this medication. It is also not recommended for individuals with severe infections such as tuberculosis, sepsis, or any other infections. Additionally, those with a weakened immune system should avoid this medication. If you experience moderate to severe heart failure, refrain from using this treatment. Should you have an active infection, inform your healthcare provider prior to starting any therapy.
Before initiating any treatment, it is crucial to inform your doctor if you have any heart, liver, or kidney problems. Children aged six or younger should consult their physician before taking Humimab HC 40mg Injection. Elderly patients over the age of 65 are at a higher risk of infections while using this medication, so it is essential to monitor any side effects they may experience. It is advisable to ensure that your child is up to date with their vaccinations to minimize the risk of infections.
The necessity of using Humimab HC 40mg Injection during pregnancy and breastfeeding will be assessed by your doctor only if it is deemed absolutely necessary, as it may lead to infections in the child. Effective contraceptive methods are recommended during treatment and for five months following its completion. Notify your doctor if you are pregnant or planning to conceive to discuss suitable contraceptive options. It is vital to inform your physician about all medications, over-the-counter drugs, vitamins, and herbal supplements you are currently taking before beginning therapy. Patients receiving Humimab HC 40mg Injection should be closely monitored by their healthcare provider for any potential side effects.
Humimab HC 40mg Injection is used in the treatment of the following:
Rheumatoid arthritis
Polyarticular juvenile idiopathic arthritis
Enthesitis-related arthritis
Ankylosing spondylitis
Axial spondyloarthritis without radiographic evidence of ankylosing spondylitis
Psoriatic arthritis
Plaque psoriasis
Hidradenitis suppurativa
Crohn’s disease
Ulcerative colitis
Non-infectious uveitis
Humimab HC 40mg Injection restricts TNF-alpha's ability to connect with its receptors, which in turn prevents TNF-alpha from mediating downstream signaling pathways. The inflammatory response, which includes immune cell activation, inflammatory cytokine generation, and recruitment of inflammatory cells to inflammatory areas, is largely regulated by these signaling pathways. By restricting the signaling pathway it decreases inflammation in various autoimmune diseases.
Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Humimab HC 40mg Injection and reduce effectiveness by causing undesirable side effects. Live vaccines must not be concurrently used along with Humimab HC 40mg Injection.
Humimab HC 40mg Injection is administered by injection under the skin (subcutaneously). The dosage and frequency of Humimab HC 40mg Injection will depend on various factors, including the patient's age, weight, overall health, and the type and stage of disease being treated. It's important to follow the dosing instructions provided by a healthcare provider, and not to adjust the dosage or frequency without consulting with them first. This medicine is to be administered by injection under the skin (subcutaneously). Your doctor or other healthcare professional will train you on how to use this injection. Do not self-administer this injection until you get trained.
If a dose is missed, it should be taken as soon as possible unless it's within 6 hours of the next scheduled dose. In that case, the missed dose should be skipped, and the regular dosing schedule should be resumed. It's important not to take a double dose of Humimab HC 40mg Injection to make up for a missed dose.
Store in a refrigerator (2°C – 8°C).
Do not freeze.
Protect the medicine from light and excessive moisture.
Keep the medicine out of reach of children and pets
It is important to get the dose at the scheduled time. If you missed the schedule, contact your doctor and reschedule the dose.
Common:
Injection site reactions
Rash
Headache
Sinusitis
Upper respiratory infections
Fever
Serious:
Heart problems
Abnormal heart beat
Severe skin reactions
GI bleeding
Abnormal blood count values
Liver injury
Bone problems
Infections
Severe respiratory problems
If you have been prescribed Humimab HC 40mg Injection or any other medication, it is crucial to adhere to the guidelines provided by your healthcare provider and to promptly report any side effects or concerns. Even if you feel an improvement or notice a change in your symptoms, it is essential to consult your doctor before discontinuing Humimab HC 40mg Injection. Regular monitoring of your blood counts is recommended. Incorporate anti-inflammatory foods into your diet, such as olive oil, nuts, seeds, fruits, vegetables, and fatty fish.
Incorporate foods like avocados, almonds, seeds, and olive oil into your diet as sources of healthy fats. These fats can enhance overall health by reducing inflammation. To maintain hydration, drink plenty of water throughout the day.
Consult your physician prior to receiving any vaccinations, as some may cause illness and should not be given while you are on this medication. If you currently have or have ever had hepatitis B, inform your doctor, as this medication may increase the likelihood of the illness recurring. You may receive guidance on how to administer medication at home. Before giving yourself an injection, ensure you fully understand all the instructions. Each time you self-administer a shot, use a different area of your body. Keep track of where you inject to ensure you rotate body parts. It is not advisable to inject into areas of skin that are hard, tender, bruised, or red.
5. Axial spondyloarthritis without radiographic evidence of ankylosing spondylitis
6. Psoriatic arthritis
7. Plaque psoriasis
8. Hidradenitis suppurativa
9. Crohn’s disease
10. Ulcerative colitis
11. Non-infectious uveitis
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